Cart
sales@molnova.com
Sodium etidronate
CAS No. 7414-83-7
Sodium etidronate( Etidronic Acid | Didronel | HEDP | Hydroxyethylidene Diphosphonic Acid )
Catalog No. M15829 CAS No. 7414-83-7
A diphosphonate which affects calcium metabolism. It inhibits ectopic calcification and slows down bone resorption and bone turnover.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 500MG | 38 | In Stock |
|
| 1G | 59 | In Stock |
|
Biological Information
-
Product NameSodium etidronate
-
NoteResearch use only, not for human use.
-
Brief DescriptionA diphosphonate which affects calcium metabolism. It inhibits ectopic calcification and slows down bone resorption and bone turnover.
-
DescriptionA diphosphonate which affects calcium metabolism. It inhibits ectopic calcification and slows down bone resorption and bone turnover. (In Vitro):Etidronic acid (Etidronate) (10 mM, 24 h) disodium shows cytotoxicity, causes a decrease in the S-phase population and an increase in the G2/M population, induces p53 mutation in MCF-7 cells.Etidronic acid (100 nM, 24 h) disodium induces osteoclast apoptosis, which displays characteristics of apoptosis, including chromatin condensation and changed cellular and nuclear morphology, detected by fluorescence microscopy.
-
In VitroEtidronic acid (Etidronate) (10 mM, 24 h) disodium shows cytotoxicity, causes a decrease in the S-phase population and an increase in the G2/M population, induces p53 mutation in MCF-7 cells.Etidronic acid (100 nM, 24 h) disodium induces osteoclast apoptosis, which displays characteristics of apoptosis, including chromatin condensation and changed cellular and nuclear morphology, detected by fluorescence microscopy.
-
In Vivo——
-
SynonymsEtidronic Acid | Didronel | HEDP | Hydroxyethylidene Diphosphonic Acid
-
PathwayProteasome/Ubiquitin
-
TargetTyrosinase
-
Recptorprotein tyrosine phosphatase
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number7414-83-7
-
Formula Weight249.99
-
Molecular FormulaC2H6Na2O7P2
-
Purity>98% (HPLC)
-
SolubilityWater: 11.5 mg/mL
-
SMILESCC(O)(P(O)(O)=O)P(O)(O)=O
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.Grases F, et al. Circ J. 2007 Jul; 71(7):1152-6.
molnova catalog
related products
-
Etarotene
Etarotene (Arotinoid ethyl sulphone) is an ethylsulfonyl derivative of aloe acid with differentiation-inducing and potentially antitumor activity.Etarotene is a collagenase inhibitor and can be used to study psoriasis.
-
RO495
RO495, a potent inhibitor of TYK2, inhibits TYK2 with IC50 of 1.5nM as tested in cell-based pharmacological assays.
-
Oxyresveratrol 3-O-β...
Oxyresveratrol 3'-O-β-D-glucopyranoside is a phenolic compound isolated from Morus nigra root and is an effective tyrosinase inhibitor with an IC50 of 1.64 μM.
